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Coadministration of FTY720 and rt-PA in an experimental model of large hemispheric stroke–no influence on functional outcome and blood–brain barrier disruption
BACKGROUND: Systemic thrombolysis with recombinant tissue plasminogen activator (rt-PA) is the standard of acute stroke care. Its potential to increase the risk of secondary intracerebral hemorrhage, especially if administered late, has been ascribed to its proteolytic activity that has detrimental...
Autores principales: | Cai, Aijia, Schlunk, Frieder, Bohmann, Ferdinand, Kashefiolasl, Sepide, Brunkhorst, Robert, Foerch, Christian, Pfeilschifter, Waltraud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029477/ https://www.ncbi.nlm.nih.gov/pubmed/24499647 http://dx.doi.org/10.1186/2040-7378-5-11 |
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