Evaluation of nasal symptoms induced by platelet activating factor, after nasal challenge in both healthy and allergic rhinitis subjects pretreated with rupatadine, levocetirizine or placebo in a cross-over study design

BACKGROUND: Platelet-activating factor (PAF) is produced by most inflammatory cells and it is involved in inflammatory and allergic reactions. We aimed to assess the anti-PAF effects of rupatadine and levocetirizine in the upper airways. FINDINGS: Healthy volunteers (HV, N = 10) and seasonal allergi...

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Detalles Bibliográficos
Autores principales: Muñoz-Cano, Rosa, Valero, Antonio, Izquierdo, Ignacio, Sánchez-López, Jaume, Doménech, Alejandro, Bartra, Joan, Mullol, Joaquim, Picado, Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029526/
https://www.ncbi.nlm.nih.gov/pubmed/24499312
http://dx.doi.org/10.1186/1710-1492-9-43

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