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Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development

Drug discovery and development to date has relied on animal models, which are useful but are often expensive, slow, and fail to mimic human physiology. The discovery of human induced pluripotent stem (iPS) cells has led to the emergence of a new paradigm of drug screening using human and disease-spe...

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Detalles Bibliográficos
Autores principales: Mathur, Anurag, Loskill, Peter, Hong, SoonGweon, Lee, Jae Young, Marcus, Sivan G, Dumont, Laure, Conklin, Bruce R, Willenbring, Holger, Lee, Luke P, Healy, Kevin E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029618/
https://www.ncbi.nlm.nih.gov/pubmed/24565415
http://dx.doi.org/10.1186/scrt375