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Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development
Drug discovery and development to date has relied on animal models, which are useful but are often expensive, slow, and fail to mimic human physiology. The discovery of human induced pluripotent stem (iPS) cells has led to the emergence of a new paradigm of drug screening using human and disease-spe...
Autores principales: | Mathur, Anurag, Loskill, Peter, Hong, SoonGweon, Lee, Jae Young, Marcus, Sivan G, Dumont, Laure, Conklin, Bruce R, Willenbring, Holger, Lee, Luke P, Healy, Kevin E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029618/ https://www.ncbi.nlm.nih.gov/pubmed/24565415 http://dx.doi.org/10.1186/scrt375 |
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