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Modulated Expression of Genes Encoding Estrogen Metabolizing Enzymes by G1-Phase Cyclin-Dependent Kinases 6 and 4 in Human Breast Cancer Cells

G1-phase cell cycle defects, such as alterations in cyclin D1 or cyclin-dependent kinase (cdk) levels, are seen in most tumors. For example, increased cyclin D1 and decreased cdk6 levels are seen in many human breast tumors. Overexpression of cdk6 in breast tumor cells in culture has been shown to s...

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Detalles Bibliográficos
Autores principales:	Jia, Yi, Domenico, Joanne, Swasey, Christina, Wang, Meiqin, Gelfand, Erwin W., Lucas, Joseph J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029737/ https://www.ncbi.nlm.nih.gov/pubmed/24848372 http://dx.doi.org/10.1371/journal.pone.0097448

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