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IQGAP3 Promotes EGFR-ERK Signaling and the Growth and Metastasis of Lung Cancer Cells

Proteins of the IQGAP family display complicated and often contradictory activities in tumorigenesis. IQGAP1 has well documented oncogenic potential and IQGAP2 has putative tumor-suppressive function. IQGAP3 is the latest addition to this family and its role in cancer development remains to be defin...

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Detalles Bibliográficos
Autores principales: Yang, Ying, Zhao, Wei, Xu, Qing-Wen, Wang, Xiao-Song, Zhang, Yu, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029748/
https://www.ncbi.nlm.nih.gov/pubmed/24849319
http://dx.doi.org/10.1371/journal.pone.0097578