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Establishment of Lipofection for Studying miRNA Function in Human Adipocytes
miRNA dysregulation has recently been linked to human obesity and its related complications such as type 2 diabetes. In order to study miRNA function in human adipocytes, we aimed for the modulation of mature miRNA concentration in these cells. Adipocytes, however, tend to be resistant to transfecti...
Autores principales: | Enlund, Eveliina, Fischer, Simon, Handrick, René, Otte, Kerstin, Debatin, Klaus-Michael, Wabitsch, Martin, Fischer-Posovszky, Pamela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029777/ https://www.ncbi.nlm.nih.gov/pubmed/24849298 http://dx.doi.org/10.1371/journal.pone.0098023 |
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