Cargando…
Rac1-Dependent Lamellipodial Motility in Prostate Cancer PC-3 Cells Revealed by Optogenetic Control of Rac1 Activity
The lamellipodium, an essential structure for cell migration, plays an important role in the invasion and metastasis of cancer cells. Although Rac1 recognized as a key player in the formation of lamellipodia, the molecular mechanisms underlying lamellipodial motility are not fully understood. Optoge...
Autores principales: | Kato, Takuma, Kawai, Katsuhisa, Egami, Youhei, Kakehi, Yoshiyuki, Araki, Nobukazu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029798/ https://www.ncbi.nlm.nih.gov/pubmed/24848679 http://dx.doi.org/10.1371/journal.pone.0097749 |
Ejemplares similares
-
Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation
por: Fujii, Makoto, et al.
Publicado: (2013) -
Rab35 Targeting to the Plasma Membrane Is Dependent on the C-terminal Polybasic Cluster
por: Kawai, Katsuhisa, et al.
Publicado: (2020) -
srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity
por: Yamazaki, Daisuke, et al.
Publicado: (2013) -
Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages
por: Kawai, Katsuhisa, et al.
Publicado: (2021) -
Optogenetic dissection of Rac1 and Cdc42 gradient shaping
por: de Beco, S., et al.
Publicado: (2018)