Rapid Renal Alpha-1 Antitrypsin Gene Induction in Experimental and Clinical Acute Kidney Injury

Alpha-1-antitrypsin (AAT) is a hepatic stress protein with protease inhibitor activity. Recent evidence indicates that ischemic or toxic injury can evoke selective changes within kidney that resemble a hepatic phenotype. Hence, we tested the following: i) Does acute kidney injury (AKI) up-regulate t...

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Detalles Bibliográficos
Autores principales: Zager, Richard A., Johnson, Ali C. M., Frostad, Kirsten B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029978/
https://www.ncbi.nlm.nih.gov/pubmed/24848503
http://dx.doi.org/10.1371/journal.pone.0098380

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