Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury

BACKGROUND: Astrogliosis is a common phenomenon after spinal cord injury (SCI). Although this process exerts positive effects on axonal regeneration, excessive astrogliosis imparts negative effects on neuronal repair and recovery. Epidermal growth factor receptor (EGFR) pathway is critical to the re...

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Detalles Bibliográficos
Autores principales: Li, Zai-Wang, Li, Ji-Jun, Wang, Lan, Zhang, Jian-Ping, Wu, Jing-Jing, Mao, Xu-Qiang, Shi, Guo-Feng, Wang, Qian, Wang, Feng, Zou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030311/
https://www.ncbi.nlm.nih.gov/pubmed/24708754
http://dx.doi.org/10.1186/1742-2094-11-71

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