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dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients
Adolescence is a period of heightened susceptibility to psychiatric disorders of medial prefrontal cortex (mPFC) dysfunction and cognitive impairment. mPFC dopamine (DA) projections reach maturity only in early adulthood, when their control over cognition becomes fully functional. The mechanisms gov...
Autores principales: | Manitt, C, Eng, C, Pokinko, M, Ryan, R T, Torres-Berrío, A, Lopez, J P, Yogendran, S V, Daubaras, M J J, Grant, A, Schmidt, E R E, Tronche, F, Krimpenfort, P, Cooper, H M, Pasterkamp, R J, Kolb, B, Turecki, G, Wong, T P, Nestler, E J, Giros, B, Flores, C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030324/ https://www.ncbi.nlm.nih.gov/pubmed/24346136 http://dx.doi.org/10.1038/tp.2013.105 |
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