Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?

Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopatho...

Descripción completa

Detalles Bibliográficos
Autores principales: Gayen, Tirthankar, Das, Anupam, Roy, Sudipta, Biswas, Shamick, Shome, Kaushik, Chowdhury, Satyendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030349/
https://www.ncbi.nlm.nih.gov/pubmed/24860756
http://dx.doi.org/10.4103/2229-5178.131094
_version_ 1782317380541612032
author Gayen, Tirthankar
Das, Anupam
Roy, Sudipta
Biswas, Shamick
Shome, Kaushik
Chowdhury, Satyendra N.
author_facet Gayen, Tirthankar
Das, Anupam
Roy, Sudipta
Biswas, Shamick
Shome, Kaushik
Chowdhury, Satyendra N.
author_sort Gayen, Tirthankar
collection PubMed
description Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopathological findings on hematoxylin and eosin and Verhoeff-Van Gieson (VVG) staining were classical of PXE. In addition to this, renal calcification was documented on plain radiography of kidneys, ureters, and bladder (KUB) in both the cases. Paucity of literature describing the association of nephrocalcinosis with PXE prompted the present report.
format Online
Article
Text
id pubmed-4030349
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-40303492014-05-23 Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation? Gayen, Tirthankar Das, Anupam Roy, Sudipta Biswas, Shamick Shome, Kaushik Chowdhury, Satyendra N. Indian Dermatol Online J Case Report Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopathological findings on hematoxylin and eosin and Verhoeff-Van Gieson (VVG) staining were classical of PXE. In addition to this, renal calcification was documented on plain radiography of kidneys, ureters, and bladder (KUB) in both the cases. Paucity of literature describing the association of nephrocalcinosis with PXE prompted the present report. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4030349/ /pubmed/24860756 http://dx.doi.org/10.4103/2229-5178.131094 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gayen, Tirthankar
Das, Anupam
Roy, Sudipta
Biswas, Shamick
Shome, Kaushik
Chowdhury, Satyendra N.
Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
title Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
title_full Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
title_fullStr Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
title_full_unstemmed Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
title_short Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?
title_sort pseudoxanthoma elasticum and nephrocalcinosis: incidental finding or an infrequent manifestation?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030349/
https://www.ncbi.nlm.nih.gov/pubmed/24860756
http://dx.doi.org/10.4103/2229-5178.131094
work_keys_str_mv AT gayentirthankar pseudoxanthomaelasticumandnephrocalcinosisincidentalfindingoraninfrequentmanifestation
AT dasanupam pseudoxanthomaelasticumandnephrocalcinosisincidentalfindingoraninfrequentmanifestation
AT roysudipta pseudoxanthomaelasticumandnephrocalcinosisincidentalfindingoraninfrequentmanifestation
AT biswasshamick pseudoxanthomaelasticumandnephrocalcinosisincidentalfindingoraninfrequentmanifestation
AT shomekaushik pseudoxanthomaelasticumandnephrocalcinosisincidentalfindingoraninfrequentmanifestation
AT chowdhurysatyendran pseudoxanthomaelasticumandnephrocalcinosisincidentalfindingoraninfrequentmanifestation

Ejemplares similares