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Hsp70 chaperones are non-equilibrium machines that achieve ultra-affinity by energy consumption
70-kDa Heat shock proteins are ATP-driven molecular chaperones that perform a myriad of essential cellular tasks. Although structural and biochemical studies have shed some light on their functional mechanism, the fundamental issue of the role of energy consumption, due to ATP-hydrolysis, has remain...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030575/ https://www.ncbi.nlm.nih.gov/pubmed/24867638 http://dx.doi.org/10.7554/eLife.02218 |