A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort

Glaucoma is a major cause of blindness in the world. To date, common genetic variants associated with glaucoma only explain a small proportion of its heritability. We performed a genome-wide association study of intra-ocular pressure (IOP), an underlying endophenotype for glaucoma. The discovery pha...

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Detalles Bibliográficos
Autores principales: Nag, Abhishek, Venturini, Cristina, Small, Kerrin S., Young, Terri L., Viswanathan, Ananth C., Mackey, David A., Hysi, Pirro G., Hammond, Christopher, Aung, Tin, Cheng, Ching-Yu, Fleck, Brian W, Gibson, Jane, Hewitt, Alex W, Hofman, Albert, Höhn, René, Jonas, Jost B, Khor, Chiea-Cheun, Klaver, Caroline CW, Lemij, Hans G, Liao, Jiemin, Lotery, Andrew J, Lu, Yi, Macgregor, Stuart, Mitchell, Paul, Ramdas, Wishal D, Springelkamp, Henriët, Tai, E-Shyong, Teo, Yik-Ying, Uitterlinden, André G, van Duijn, Cornelia M, van Koolwijk, Leonieke ME, Vingerling, Johannes R, Vitart, Veronique, Vithana, Eranga, Wang, Jie Jin, Williams, Katie M, Wojciechowski, Robert, Wong, Tien-Yin, Xu, Liang, Yonova-Doing, Ekaterina, Tanja, Zeller
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030784/
https://www.ncbi.nlm.nih.gov/pubmed/24518671
http://dx.doi.org/10.1093/hmg/ddu050

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