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Control of Collagen Stability and Heterotrimer Specificity through Repulsive Electrostatic Interactions
Charge-pair interactions between acidic and basic residues on the surface of collagen can promote stability as well as control specificity of molecular recognition. Heterotrimeric collagen peptides have been engineered de novo using either rational or computational methods, which in both cases optim...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030969/ https://www.ncbi.nlm.nih.gov/pubmed/24970200 http://dx.doi.org/10.3390/biom3040986 |