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The Mucoid Switch in Pseudomonas aeruginosa Represses Quorum Sensing Systems and Leads to Complex Changes to Stationary Phase Virulence Factor Regulation

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the airways of Cystic Fibrosis (CF) patients during which it adapts and undergoes clonal expansion within the lung. It commonly acquires inactivating mutations of the anti-sigma factor MucA leading to a mucoid phenotype, caused by...

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Detalles Bibliográficos
Autores principales:	Ryall, Ben, Carrara, Marta, Zlosnik, James E. A., Behrends, Volker, Lee, Xiaoyun, Wong, Zhen, Lougheed, Kathryn E., Williams, Huw D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031085/ https://www.ncbi.nlm.nih.gov/pubmed/24852379 http://dx.doi.org/10.1371/journal.pone.0096166

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