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The Mucoid Switch in Pseudomonas aeruginosa Represses Quorum Sensing Systems and Leads to Complex Changes to Stationary Phase Virulence Factor Regulation

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the airways of Cystic Fibrosis (CF) patients during which it adapts and undergoes clonal expansion within the lung. It commonly acquires inactivating mutations of the anti-sigma factor MucA leading to a mucoid phenotype, caused by...

תיאור מלא

מידע ביבליוגרפי
Autores principales: Ryall, Ben, Carrara, Marta, Zlosnik, James E. A., Behrends, Volker, Lee, Xiaoyun, Wong, Zhen, Lougheed, Kathryn E., Williams, Huw D.
פורמט: Online Artículo Texto
שפה:English
יצא לאור: Public Library of Science 2014
נושאים:
גישה מקוונת:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031085/
https://www.ncbi.nlm.nih.gov/pubmed/24852379
http://dx.doi.org/10.1371/journal.pone.0096166