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Novel Epigenetic Target Therapy for Prostate Cancer: A Preclinical Study

Epigenetic events are critical contributors to the pathogenesis of cancer, and targeting epigenetic mechanisms represents a novel strategy in anticancer therapy. Classic demethylating agents, such as 5-Aza-2′-deoxycytidine (Decitabine), hold the potential for reprograming somatic cancer cells demons...

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Detalles Bibliográficos
Autores principales: Naldi, Ilaria, Taranta, Monia, Gherardini, Lisa, Pelosi, Gualtiero, Viglione, Federica, Grimaldi, Settimio, Pani, Luca, Cinti, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031137/
https://www.ncbi.nlm.nih.gov/pubmed/24851905
http://dx.doi.org/10.1371/journal.pone.0098101