Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity

Mammalian sterile 20-like kinase 1 (Mst1) is a MAPK kinase kinase kinase which is involved in a wide range of cellular responses, including apoptosis, lymphocyte adhesion and trafficking. The contribution of Mst1 to Ag-specific immune responses and autoimmunity has not been well defined. In this stu...

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Detalles Bibliográficos
Autores principales: Salojin, Konstantin V., Hamman, Brian D., Chang, Wei Chun, Jhaver, Kanchan G., Al-Shami, Amin, Crisostomo, Jeannette, Wilkins, Carrie, Digeorge-Foushee, Ann Marie, Allen, Jason, Patel, Nita, Gopinathan, Suma, Zhou, Julia, Nouraldeen, Amr, Jessop, Theodore C., Bagdanoff, Jeffrey T., Augeri, David J., Read, Robert, Vogel, Peter, Swaffield, Jonathan, Wilson, Alan, Platt, Kenneth A., Carson, Kenneth G., Main, Alan, Zambrowicz, Brian P., Oravecz, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031148/
https://www.ncbi.nlm.nih.gov/pubmed/24852423
http://dx.doi.org/10.1371/journal.pone.0098151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031148/
https://www.ncbi.nlm.nih.gov/pubmed/24852423
http://dx.doi.org/10.1371/journal.pone.0098151

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