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Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity
Mammalian sterile 20-like kinase 1 (Mst1) is a MAPK kinase kinase kinase which is involved in a wide range of cellular responses, including apoptosis, lymphocyte adhesion and trafficking. The contribution of Mst1 to Ag-specific immune responses and autoimmunity has not been well defined. In this stu...
Autores principales: | Salojin, Konstantin V., Hamman, Brian D., Chang, Wei Chun, Jhaver, Kanchan G., Al-Shami, Amin, Crisostomo, Jeannette, Wilkins, Carrie, Digeorge-Foushee, Ann Marie, Allen, Jason, Patel, Nita, Gopinathan, Suma, Zhou, Julia, Nouraldeen, Amr, Jessop, Theodore C., Bagdanoff, Jeffrey T., Augeri, David J., Read, Robert, Vogel, Peter, Swaffield, Jonathan, Wilson, Alan, Platt, Kenneth A., Carson, Kenneth G., Main, Alan, Zambrowicz, Brian P., Oravecz, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031148/ https://www.ncbi.nlm.nih.gov/pubmed/24852423 http://dx.doi.org/10.1371/journal.pone.0098151 |
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