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G1 checkpoint establishment in vivo during embryonic liver development

BACKGROUND: The DNA damage-mediated cell cycle checkpoint is an essential mechanism in the DNA damage response (DDR). During embryonic development, the characteristics of cell cycle and DNA damage checkpoint evolve from an extremely short G1 cell phase and lacking G1 checkpoint to lengthening G1 pha...

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Detalles Bibliográficos
Autores principales: Wang, Xiao Qi, Chan, Kwok Kin, Ming, Xiaoyan, Lui, Vincent CH, Poon, Randy YC, Lo, Chung Mau, Norbury, Chris, Poon, Ronnie TP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031160/
https://www.ncbi.nlm.nih.gov/pubmed/24886500
http://dx.doi.org/10.1186/1471-213X-14-23

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