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Recombinant fusion protein of cholera toxin B subunit with YVAD secreted by Lactobacillus casei inhibits lipopolysaccharide-induced caspase-1 activation and subsequent IL-1 beta secretion in Caco-2 cells
BACKGROUND: Lactobacillus species are used as bacterial vectors to deliver functional peptides to the intestine because they are delivered live to the intestine, colonize the mucosal surface, and continue to produce the desired protein. Previously, we generated a recombinant Lactobacillus casei secr...
Autores principales: | Hiramatsu, Yukihiro, Yamamoto, Masatatsu, Satho, Tomomitsu, Irie, Keiichi, Kai, Akiko, Uyeda, Saori, Fukumitsu, Yuki, Toda, Akihisa, Miyata, Takeshi, Miake, Fumio, Arakawa, Takeshi, Kashige, Nobuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031163/ https://www.ncbi.nlm.nih.gov/pubmed/24884459 http://dx.doi.org/10.1186/1472-6750-14-38 |
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