Cargando…

PARP-1 Val762Ala Polymorphism and Risk of Cancer: A Meta-Analysis Based on 39 Case-Control Studies

BACKGROUND: Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear chromatin-associated enzyme involved in several important cellular processes, particularly in the DNA repair system. PARP-1 rs1136410: C>T is among the most studied polymorphisms and likely involved in human carcinogenesis. However,...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Qin, Lu, Jing, Zhu, Hongcheng, Xu, Liping, Cheng, Hongyan, Zhan, Liangliang, Yang, Xi, Zhang, Chi, Sun, Xinchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031170/
https://www.ncbi.nlm.nih.gov/pubmed/24853559
http://dx.doi.org/10.1371/journal.pone.0098022