Prostacyclin Analogue Beraprost Inhibits Cardiac Fibroblast Proliferation Depending on Prostacyclin Receptor Activation through a TGF β-Smad Signal Pathway

Previous studies showed that prostacyclin inhibited fibrosis. However, both receptors of prostacyclin, prostacyclin receptor (IP) and peroxisome proliferator-activated receptor (PPAR), are abundant in cardiac fibroblasts. Here we investigated which receptor was vital in the anti-fibrosis effect of p...

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Detalles Bibliográficos
Autores principales: Chen, Yun, Yang, Shengju, Yao, Wenjuan, Zhu, Hongyan, Xu, Xiaole, Meng, Guoliang, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031177/
https://www.ncbi.nlm.nih.gov/pubmed/24852754
http://dx.doi.org/10.1371/journal.pone.0098483

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