TNFα and IFNγ but Not Perforin Are Critical for CD8 T Cell-Mediated Protection against Pulmonary Yersinia pestis Infection

Septic pneumonias resulting from bacterial infections of the lung are a leading cause of human death worldwide. Little is known about the capacity of CD8 T cell-mediated immunity to combat these infections and the types of effector functions that may be most effective. Pneumonic plague is an acutely...

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Detalles Bibliográficos
Autores principales: Szaba, Frank M., Kummer, Lawrence W., Duso, Debra K., Koroleva, Ekaterina P., Tumanov, Alexei V., Cooper, Andrea M., Bliska, James B., Smiley, Stephen T., Lin, Jr-Shiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031182/
https://www.ncbi.nlm.nih.gov/pubmed/24854422
http://dx.doi.org/10.1371/journal.ppat.1004142

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