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Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography

PURPOSE: To compare corneal thickness measurements using Pentacam (Oculus, Germany), Sirius (CSO, Italy), Galilei (Ziemer, Switzerland), and RTVue-100 OCT (Optovue Inc., USA). METHODS: Sixty-six eyes of 66 healthy volunteers were enrolled. Three consecutive measurements were performed with each devi...

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Autores principales: Huang, Jinhai, Ding, Xixia, Savini, Giacomo, Jiang, Zhengxuan, Pan, Chao, Hua, Yanjun, Wu, Fan, Feng, Yifan, Yu, Ye, Wang, Qinmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031212/
https://www.ncbi.nlm.nih.gov/pubmed/24854348
http://dx.doi.org/10.1371/journal.pone.0098316
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author Huang, Jinhai
Ding, Xixia
Savini, Giacomo
Jiang, Zhengxuan
Pan, Chao
Hua, Yanjun
Wu, Fan
Feng, Yifan
Yu, Ye
Wang, Qinmei
author_facet Huang, Jinhai
Ding, Xixia
Savini, Giacomo
Jiang, Zhengxuan
Pan, Chao
Hua, Yanjun
Wu, Fan
Feng, Yifan
Yu, Ye
Wang, Qinmei
author_sort Huang, Jinhai
collection PubMed
description PURPOSE: To compare corneal thickness measurements using Pentacam (Oculus, Germany), Sirius (CSO, Italy), Galilei (Ziemer, Switzerland), and RTVue-100 OCT (Optovue Inc., USA). METHODS: Sixty-six eyes of 66 healthy volunteers were enrolled. Three consecutive measurements were performed with each device. The mean value of the three measurements was used for subsequent analysis. Central corneal thickness (CCT), thinnest corneal thickness (TCT), and midperipheral corneal thickness (MPCT; measured at superior, inferior, nasal, and temporal locations with a distance of 1 mm (CT(2mm)) or 2.5 mm (CT(5mm)) from the corneal apex) were analyzed. Differences and agreement between measurements were assessed using the repeated-measures analysis of variance (ANOVA) and Bland-Altman analyses, respectively. RESULTS: Statistically significant differences (p<0.001) among the four devices were revealed in CCT, TCT and CT(2mm)measurements. The CCT, TCT, and CT(2mm) values were ranked from the thickest to the thinnest as follows: Galilei>Sirius>Pentacam>RTVue OCT. For these measurements, agreement between measurements by Sirius and Pentacam was good, whereas Galilei overestimated and RTVue underestimated corneal thickness compared to Sirius and Pentacam. As regards CT(5mm) measurements, Pentacam provided the largest values, whereas RTVue OCT yielded the smallest values. Agreement of the CT(5mm) measurements was good between the Pentacam, Sirius, moderate between Galilei and the other two Scheimpflug systems, and poor between the RTVue OCT and the remaining devices. CONCLUSIONS: The Pentacam and Sirius can be used interchangeably for CCT measurements, while the Galilei and RTVue systematically over- and underestimate CCT, respectively. The three Scheimpflug cameras, but not the RTVue, may be used interchangeably for MPCT measurements.
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spelling pubmed-40312122014-05-28 Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography Huang, Jinhai Ding, Xixia Savini, Giacomo Jiang, Zhengxuan Pan, Chao Hua, Yanjun Wu, Fan Feng, Yifan Yu, Ye Wang, Qinmei PLoS One Research Article PURPOSE: To compare corneal thickness measurements using Pentacam (Oculus, Germany), Sirius (CSO, Italy), Galilei (Ziemer, Switzerland), and RTVue-100 OCT (Optovue Inc., USA). METHODS: Sixty-six eyes of 66 healthy volunteers were enrolled. Three consecutive measurements were performed with each device. The mean value of the three measurements was used for subsequent analysis. Central corneal thickness (CCT), thinnest corneal thickness (TCT), and midperipheral corneal thickness (MPCT; measured at superior, inferior, nasal, and temporal locations with a distance of 1 mm (CT(2mm)) or 2.5 mm (CT(5mm)) from the corneal apex) were analyzed. Differences and agreement between measurements were assessed using the repeated-measures analysis of variance (ANOVA) and Bland-Altman analyses, respectively. RESULTS: Statistically significant differences (p<0.001) among the four devices were revealed in CCT, TCT and CT(2mm)measurements. The CCT, TCT, and CT(2mm) values were ranked from the thickest to the thinnest as follows: Galilei>Sirius>Pentacam>RTVue OCT. For these measurements, agreement between measurements by Sirius and Pentacam was good, whereas Galilei overestimated and RTVue underestimated corneal thickness compared to Sirius and Pentacam. As regards CT(5mm) measurements, Pentacam provided the largest values, whereas RTVue OCT yielded the smallest values. Agreement of the CT(5mm) measurements was good between the Pentacam, Sirius, moderate between Galilei and the other two Scheimpflug systems, and poor between the RTVue OCT and the remaining devices. CONCLUSIONS: The Pentacam and Sirius can be used interchangeably for CCT measurements, while the Galilei and RTVue systematically over- and underestimate CCT, respectively. The three Scheimpflug cameras, but not the RTVue, may be used interchangeably for MPCT measurements. Public Library of Science 2014-05-22 /pmc/articles/PMC4031212/ /pubmed/24854348 http://dx.doi.org/10.1371/journal.pone.0098316 Text en © 2014 Huang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Huang, Jinhai
Ding, Xixia
Savini, Giacomo
Jiang, Zhengxuan
Pan, Chao
Hua, Yanjun
Wu, Fan
Feng, Yifan
Yu, Ye
Wang, Qinmei
Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography
title Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography
title_full Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography
title_fullStr Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography
title_full_unstemmed Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography
title_short Central and Midperipheral Corneal Thickness Measured with Scheimpflug Imaging and Optical Coherence Tomography
title_sort central and midperipheral corneal thickness measured with scheimpflug imaging and optical coherence tomography
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031212/
https://www.ncbi.nlm.nih.gov/pubmed/24854348
http://dx.doi.org/10.1371/journal.pone.0098316
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