Cargando…

Transcription activator-like effector nuclease-mediated transduction of exogenous gene into IL2RG locus

X-linked severe combined immunodeficiency (SCID-X1) caused by mutations in interleukin 2 receptor gamma (IL2RG) gene threatens the survival of affected boys during the first year of life unless hematopoietic stem cell transplantation is provided. Although viral vector-mediated gene therapy has been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsubara, Yohei, Chiba, Tomoki, Kashimada, Kenichi, Morio, Tomohiro, Takada, Shuji, Mizutani, Shuki, Asahara, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031469/ https://www.ncbi.nlm.nih.gov/pubmed/24853770 http://dx.doi.org/10.1038/srep05043

Ejemplares similares

Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases
por: Cai, Yujia, et al.
Publicado: (2014)

In Vitro Enzyme Assay of CYP21A2 Mutation (R483Q) by A Novel Method Using Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS)
por: Ono, Makoto, et al.
Publicado: (2008)

Endocrinopathies in Inborn Errors of Immunity
por: Takasawa, Kei, et al.
Publicado: (2021)

Human lactoferrin efficiently targeted into caprine beta-lactoglobulin locus with transcription activator-like effector nucleases
por: Yuan, Yu-Guo, et al.
Publicado: (2017)

EWSR1/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway
por: Endo, Akifumi, et al.
Publicado: (2016)

Adrenal suppression and anthropometric data at two years of age was not influenced by the initial hydrocortisone dose in patients with 21-hydroxylase deficiency
por: Saito, Yoko, et al.
Publicado: (2021)

Peptidyl arginine deiminase 2 (Padi2) is expressed in Sertoli cells in a specific manner and regulated by SOX9 during testicular development
por: Tsuji-Hosokawa, Atsumi, et al.
Publicado: (2018)

Comparing Zinc Finger Nucleases and Transcription Activator-Like Effector Nucleases for Gene Targeting in Drosophila
por: Beumer, Kelly J., et al.
Publicado: (2013)

Deletion of conserved sequences in IG-DMR at Dlk1-Gtl2 locus suggests their involvement in expression of paternally expressed genes in mice
por: SAITO, Takeshi, et al.
Publicado: (2016)

A novel variant of NR5A1, p.R350W implicates potential interactions with unknown co-factors or ligands
por: Gau, Maki, et al.
Publicado: (2023)

Comprehensive analysis of the specificity of transcription activator-like effector nucleases
por: Juillerat, Alexandre, et al.
Publicado: (2014)

A 45,X/46,XY DSD (Disorder of Sexual Development) case with an extremely uneven distribution of 46,XY cells between lymphocytes and gonads
por: Nomura, Risa, et al.
Publicado: (2015)

A first experience of transduction for differentiated HepaRG cells using lentiviral technology
por: Pivert, Adeline, et al.
Publicado: (2019)

Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes
por: Mashimo, Tomoji, et al.
Publicado: (2013)

Targeted Mutagenesis of Arabidopsis thaliana Using Engineered TAL Effector Nucleases
por: Christian, Michelle, et al.
Publicado: (2013)

Generation of knockout rabbits using transcription activator-like effector nucleases
por: Wang, Yu, et al.
Publicado: (2014)

RNase III nucleases from diverse kingdoms serve as antiviral effectors
por: Aguado, Lauren C., et al.
Publicado: (2017)

Nuclease-mediated gene editing by homologous recombination of the human globin locus
por: Voit, Richard A., et al.
Publicado: (2014)

Changes in electrophysiological findings of spinal muscular atrophy type I after the administration of nusinersen and onasemnogene abeparvovec: two case reports
por: Mizuno, Tomoko, et al.
Publicado: (2023)

Histone deacetylases inhibitor and RAD51 recombinase increase transcription activator-like effector nucleases-mediated homologous recombination on the bovine β-casein gene locus
por: Park, Da Som, et al.
Publicado: (2020)

Germline-Transmitted Genome Editing in Arabidopsis thaliana Using TAL-Effector-Nucleases
por: Forner, Joachim, et al.
Publicado: (2015)

Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases
por: Zhao, Xinxia, et al.
Publicado: (2016)

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases
por: Perez-Pinera, Pablo, et al.
Publicado: (2012)

Publisher Correction: A first experience of transduction for differentiated HepaRG cells using lentiviral technology
por: Pivert, Adeline, et al.
Publicado: (2021)

Newborn screening for congenital adrenal hyperplasia in Tokyo, Japan from 1989 to 2013: a retrospective population-based study
por: Tsuji, Atsumi, et al.
Publicado: (2015)

A novel COL11A1 missense mutation in siblings with non-ocular Stickler syndrome
por: Kohmoto, Tomohiro, et al.
Publicado: (2016)

Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)
por: Moore, Finola E., et al.
Publicado: (2012)

Targeting Human MicroRNA Genes Using Engineered Tal-Effector Nucleases (TALENs)
por: Hu, Ruozhen, et al.
Publicado: (2013)

Exploring the transcription activator-like effectors scaffold versatility to expand the toolbox of designer nucleases
por: Juillerat, Alexandre, et al.
Publicado: (2014)

Rh D blood group conversion using transcription activator-like effector nucleases
por: Kim, Young-Hoon, et al.
Publicado: (2015)

Correction: Germline-Transmitted Genome Editing in Arabidopsis thaliana Using TAL-Effector-Nucleases
por: Forner, Joachim, et al.
Publicado: (2015)

High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases
por: Qiu, Zhongwei, et al.
Publicado: (2013)

Novel Type V-A CRISPR Effectors Are Active Nucleases with Expanded Targeting Capabilities
por: Aliaga Goltsman, Daniela S., et al.
Publicado: (2020)

Antibacterial T6SS effectors with a VRR-Nuc domain are structure-specific nucleases
por: Hespanhol, Julia Takuno, et al.
Publicado: (2022)

Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing
por: Cristea, Sandra, et al.
Publicado: (2011)

Analysis of the Mouse Y Chromosome by Single-Molecule Sequencing With Y Chromosome Enrichment
por: Yano, Yuki, et al.
Publicado: (2020)

Perinatal factors affecting growth and development at age 3 years in extremely low birth weight infants born small for gestational age
por: Matsuda, Nozomi, et al.
Publicado: (2018)

Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
por: Li, Ting, et al.
Publicado: (2011)

Generation of gene disruptions by transcription activator-like effector nucleases (TALENs) in Xenopus tropicalis embryos
por: Lei, Yong, et al.
Publicado: (2013)

Corrigendum: Rh D blood group conversion using transcription activator-like effector nucleases
por: Kim, Young-Hoon, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_p4qsvppkhqtrcvlqimvc3v5bb2