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TGF-β1 induces senescence of bone marrow mesenchymal stem cells via increase of mitochondrial ROS production

BACKGROUND: Bone marrow derived mesenchymal stem cells (bmMSCs) are multipotent cells that can differentiate into diverse cell types, including cardiomyocytes. BmMSC-based transplantation is capable of repairing acute and chronic myocardial infarction. Prior to the transplantation, MSCs are usually...

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Detalles Bibliográficos
Autores principales:	Wu, Junfang, Niu, Jie, Li, Xiaopeng, Wang, Xianwei, Guo, Zhikun, Zhang, Fenxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031602/ https://www.ncbi.nlm.nih.gov/pubmed/24886313 http://dx.doi.org/10.1186/1471-213X-14-21

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