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Effects of Dairy on Metabolic Syndrome Parameters: A Review
Metabolic syndrome (MetS), characterized by central obesity, dyslipidemias, hypertension, and hyperglycemia, impacts 34 percent of the U.S. adult population. MetS has been demonstrated to be affected by dietary components. Data from epidemiological studies and clinical interventions suggest that one...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
YJBM
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031787/ https://www.ncbi.nlm.nih.gov/pubmed/24910559 |
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author | Dugan, Christine E. Fernandez, Maria Luz |
author_facet | Dugan, Christine E. Fernandez, Maria Luz |
author_sort | Dugan, Christine E. |
collection | PubMed |
description | Metabolic syndrome (MetS), characterized by central obesity, dyslipidemias, hypertension, and hyperglycemia, impacts 34 percent of the U.S. adult population. MetS has been demonstrated to be affected by dietary components. Data from epidemiological studies and clinical interventions suggest that one or more dairy components might directly affect MetS parameters. For example, calcium has been postulated to reduce body weight by modulating vitamin D concentrations in plasma and therefore attenuating intracellular calcium effects in activating genes involved in fatty acid synthesis and reducing those involved in lipolysis. Peptides present in milk have been associated with the inhibition of angiotensin converting enzyme and, therefore, with blood pressure reductions. Branched chain amino acids may increase post-prandial insulin secretion and regulate plasma glucose levels, and leucine, an abundant amino acid in milk, may be responsible for decreased plasma glucose through modulation of mTOR. Through different proposed mechanisms, dairy nutrients may target all components of MetS. |
format | Online Article Text |
id | pubmed-4031787 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | YJBM |
record_format | MEDLINE/PubMed |
spelling | pubmed-40317872014-06-06 Effects of Dairy on Metabolic Syndrome Parameters: A Review Dugan, Christine E. Fernandez, Maria Luz Yale J Biol Med Focus: Obesity Metabolic syndrome (MetS), characterized by central obesity, dyslipidemias, hypertension, and hyperglycemia, impacts 34 percent of the U.S. adult population. MetS has been demonstrated to be affected by dietary components. Data from epidemiological studies and clinical interventions suggest that one or more dairy components might directly affect MetS parameters. For example, calcium has been postulated to reduce body weight by modulating vitamin D concentrations in plasma and therefore attenuating intracellular calcium effects in activating genes involved in fatty acid synthesis and reducing those involved in lipolysis. Peptides present in milk have been associated with the inhibition of angiotensin converting enzyme and, therefore, with blood pressure reductions. Branched chain amino acids may increase post-prandial insulin secretion and regulate plasma glucose levels, and leucine, an abundant amino acid in milk, may be responsible for decreased plasma glucose through modulation of mTOR. Through different proposed mechanisms, dairy nutrients may target all components of MetS. YJBM 2014-06-06 /pmc/articles/PMC4031787/ /pubmed/24910559 Text en Copyright ©2014, Yale Journal of Biology and Medicine https://creativecommons.org/licenses/by-nc/3.0/This is an open access article distributed under the terms of the Creative Commons CC BY-NC license, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes. |
spellingShingle | Focus: Obesity Dugan, Christine E. Fernandez, Maria Luz Effects of Dairy on Metabolic Syndrome Parameters: A Review |
title | Effects of Dairy on Metabolic Syndrome Parameters: A Review |
title_full | Effects of Dairy on Metabolic Syndrome Parameters: A Review |
title_fullStr | Effects of Dairy on Metabolic Syndrome Parameters: A Review |
title_full_unstemmed | Effects of Dairy on Metabolic Syndrome Parameters: A Review |
title_short | Effects of Dairy on Metabolic Syndrome Parameters: A Review |
title_sort | effects of dairy on metabolic syndrome parameters: a review |
topic | Focus: Obesity |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031787/ https://www.ncbi.nlm.nih.gov/pubmed/24910559 |
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