Cargando…
Evidence from molecular dynamics simulations of conformational preorganization in the ribonuclease H active site
Ribonuclease H1 (RNase H) enzymes are well-conserved endonucleases that are present in all domains of life and are particularly important in the life cycle of retroviruses as domains within reverse transcriptase. Despite extensive study, especially of the E. coli homolog, the interaction of the high...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032109/ https://www.ncbi.nlm.nih.gov/pubmed/25075292 http://dx.doi.org/10.12688/f1000research.3605.1 |