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Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

BACKGROUND: Recombinant soluble, cleaved HIV-1 envelope glycoprotein SOSIP.664 gp140 trimers based on the subtype A BG505 sequence are being studied structurally and tested as immunogens in animals. For these trimers to become a vaccine candidate for human trials, they would need to be made in appro...

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Detalles Bibliográficos
Autores principales:	Chung, Nancy PY, Matthews, Katie, Kim, Helen J, Ketas, Thomas J, Golabek, Michael, de los Reyes, Kevin, Korzun, Jacob, Yasmeen, Anila, Sanders, Rogier W, Klasse, Per Johan, Wilson, Ian A, Ward, Andrew B, Marozsan, Andre J, Moore, John P, Cupo, Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032163/ https://www.ncbi.nlm.nih.gov/pubmed/24767177 http://dx.doi.org/10.1186/1742-4690-11-33

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