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Impaired natural killer cell responses are associated with loss of the highly activated NKG2A(+)CD57(+)CD56(dim) subset in HIV-1 subtype D infection in Uganda
OBJECTIVE: Of the predominant HIV-1 subtypes in Uganda, subtype D infection confers a worse prognosis. HIV-1 infection causes perturbations to natural killer (NK) cells, and yet these cells can exert immune pressure on the virus and influence clinical outcome. Here, we studied NK cell activation and...
Autores principales: | Naluyima, Prossy, Eller, Michael A., Laeyendecker, Oliver, Quinn, Thomas C., Serwadda, David, Sewankambo, Nelson K., Gray, Ronald H., Michael, Nelson L., Wabwire-Mangen, Fred, Robb, Merlin L., Sandberg, Johan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032214/ https://www.ncbi.nlm.nih.gov/pubmed/24959961 http://dx.doi.org/10.1097/QAD.0000000000000286 |
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