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The Hepatoselective Glucokinase Activator PF-04991532 Ameliorates Hyperglycemia without Causing Hepatic Steatosis in Diabetic Rats

Hyperglycemia resulting from type 2 diabetes mellitus (T2DM) is the main cause of diabetic complications such as retinopathy and neuropathy. A reduction in hyperglycemia has been shown to prevent these associated complications supporting the importance of glucose control. Glucokinase converts glucos...

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Detalles Bibliográficos
Autores principales:	Erion, Derek M., Lapworth, Amanda, Amor, Paul A., Bai, Guoyun, Vera, Nicholas B., Clark, Ronald W., Yan, Qingyun, Zhu, Yimin, Ross, Trenton T., Purkal, Julie, Gorgoglione, Matthew, Zhang, Guodong, Bonato, Vinicius, Baker, Levenia, Barucci, Nicole, D’Aquila, Theresa, Robertson, Alan, Aiello, Robert J., Yan, Jiangli, Trimmer, Jeff, Rolph, Timothy P., Pfefferkorn, Jeffrey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032240/ https://www.ncbi.nlm.nih.gov/pubmed/24858947 http://dx.doi.org/10.1371/journal.pone.0097139

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