Intrathecal Infusion of Hydrogen-Rich Normal Saline Attenuates Neuropathic Pain via Inhibition of Activation of Spinal Astrocytes and Microglia in Rats

BACKGROUND: Reactive oxygen and nitrogen species are key molecules that mediate neuropathic pain. Although hydrogen is an established antioxidant, its effect on chronic pain has not been characterized. This study was to investigate the efficacy and mechanisms of hydrogen-rich normal saline induced a...

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Detalles Bibliográficos
Autores principales: Ge, Yanhu, Wu, Feixiang, Sun, Xuejun, Xiang, Zhenghua, Yang, Liqun, Huang, Shengdong, Lu, Zhijie, Sun, Yuming, Yu, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032255/
https://www.ncbi.nlm.nih.gov/pubmed/24857932
http://dx.doi.org/10.1371/journal.pone.0097436

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