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Recombinant Adeno-Associated Virus: Efficient Transduction of the Rat VMH and Clearance from Blood

To promote the efficient and safe application of adeno-associated virus (AAV) vectors as a gene transfer tool in the central nervous system (CNS), transduction efficiency and clearance were studied for serotypes commonly used to transfect distinct areas of the brain. As AAV2 was shown to transduce o...

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Detalles Bibliográficos
Autores principales: van Gestel, Margriet A., Boender, Arjen J., de Vrind, Veronne A. J., Garner, Keith M., Luijendijk, Mieneke C. M., Adan, Roger A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032260/
https://www.ncbi.nlm.nih.gov/pubmed/24858547
http://dx.doi.org/10.1371/journal.pone.0097639