Cargando…
Recombinant Adeno-Associated Virus: Efficient Transduction of the Rat VMH and Clearance from Blood
To promote the efficient and safe application of adeno-associated virus (AAV) vectors as a gene transfer tool in the central nervous system (CNS), transduction efficiency and clearance were studied for serotypes commonly used to transfect distinct areas of the brain. As AAV2 was shown to transduce o...
Autores principales: | van Gestel, Margriet A., Boender, Arjen J., de Vrind, Veronne A. J., Garner, Keith M., Luijendijk, Mieneke C. M., Adan, Roger A. H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032260/ https://www.ncbi.nlm.nih.gov/pubmed/24858547 http://dx.doi.org/10.1371/journal.pone.0097639 |
Ejemplares similares
-
The obesity‐associated gene Negr1 regulates aspects of energy balance in rat hypothalamic areas
por: Boender, Arjen J., et al.
Publicado: (2014) -
Effects of GABA and Leptin Receptor‐Expressing Neurons in the Lateral Hypothalamus on Feeding, Locomotion, and Thermogenesis
por: de Vrind, Véronne A.J., et al.
Publicado: (2019) -
Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding
por: de Vrind, Véronne A. J., et al.
Publicado: (2021) -
An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector
por: de Backer, Marijke WA, et al.
Publicado: (2010) -
FTO knockdown in rat ventromedial hypothalamus does not affect energy balance
por: van Gestel, Margriet A., et al.
Publicado: (2014)