The Involvement of NFAT Transcriptional Activity Suppression in SIRT1-Mediated Inhibition of COX-2 Expression Induced by PMA/Ionomycin

SIRT1, a class III histone deacetylase, acts as a negative regulator for many transcription factors, and plays protective roles in inflammation and atherosclerosis. Transcription factor nuclear factor of activated T cells (NFAT) has been previously shown to play pro-inflammatory roles in endothelial...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Yu-Yan, Lu, Jie, Huang, Yue, Liu, Guang, Gao, Peng, Wan, Yan-Zhen, Zhang, Ran, Zhang, Zhu-Qin, Yang, Rui-Feng, Tang, Xiaoqiang, Xu, Jing, Wang, Xu, Chen, Hou-Zao, Liu, De-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032329/
https://www.ncbi.nlm.nih.gov/pubmed/24859347
http://dx.doi.org/10.1371/journal.pone.0097999

Ejemplares similares

Ejemplares similares