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NOD-scidIl2rg(tm1Wjl) and NOD-Rag1(null)Il2rg(tm1Wjl): A Model for Stromal Cell–Tumor Cell Interaction for Human Colon Cancer
BACKGROUND/AIMS: Stromal cells and the extracellular environment are vital to human tumors, influencing growth and response to therapy. Human tumor cell lines lack stroma and transplantation into immunodeficient mice does not allow meaningful analyses of the effects of stroma on tumor cell growth. S...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032472/ https://www.ncbi.nlm.nih.gov/pubmed/24798995 http://dx.doi.org/10.1007/s10620-014-3168-5 |