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NOD-scidIl2rg(tm1Wjl) and NOD-Rag1(null)Il2rg(tm1Wjl): A Model for Stromal Cell–Tumor Cell Interaction for Human Colon Cancer

BACKGROUND/AIMS: Stromal cells and the extracellular environment are vital to human tumors, influencing growth and response to therapy. Human tumor cell lines lack stroma and transplantation into immunodeficient mice does not allow meaningful analyses of the effects of stroma on tumor cell growth. S...

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Detalles Bibliográficos
Autores principales: Maykel, Justin, Liu, Jian Hua, Li, Hanchen, Shultz, Leonard D., Greiner, Dale L., Houghton, JeanMarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032472/
https://www.ncbi.nlm.nih.gov/pubmed/24798995
http://dx.doi.org/10.1007/s10620-014-3168-5