Compensatory Flux Changes within an Endocytic Trafficking Network Maintain Thermal Robustness of Notch Signaling

Developmental signaling is remarkably robust to environmental variation, including temperature. For example, in ectothermic animals such as Drosophila, Notch signaling is maintained within functional limits across a wide temperature range. We combine experimental and computational approaches to show...

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Detalles Bibliográficos
Autores principales: Shimizu, Hideyuki, Woodcock, Simon A., Wilkin, Marian B., Trubenová, Barbora, Monk, Nicholas A.M., Baron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032575/
https://www.ncbi.nlm.nih.gov/pubmed/24855951
http://dx.doi.org/10.1016/j.cell.2014.03.050

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