Cargando…

In Vitro Screening for β-Hydroxy-β-methylglutaryl-CoA Reductase Inhibitory and Antioxidant Activity of Sequentially Extracted Fractions of Ficus palmata Forsk

Hypercholesterolemia-induced oxidative stress has been strongly implicated in the pathogenesis of atherosclerosis, which is one of the major causes of mortality worldwide. The current work, for the first time, accounts the antioxidant, genoprotective, antilipoperoxidative, and HMG-CoA reductase (EC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iqbal, Danish, Khan, M. Salman, Khan, Amir, Khan, Mohd. Sajid, Ahmad, Saheem, Srivastava, Ashwani K., Bagga, Paramdeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032710/ https://www.ncbi.nlm.nih.gov/pubmed/24883325 http://dx.doi.org/10.1155/2014/762620

Ejemplares similares

Bioactivity guided fractionation and hypolipidemic property of a novel HMG-CoA reductase inhibitor from Ficus virens Ait
por: Iqbal, Danish, et al.
Publicado: (2015)

The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases
por: Friesen, Jon A, et al.
Publicado: (2004)

Expressional diversity of grapevine 3-Hydroxy-3-methylglutaryl-CoA reductase (VvHMGR) in different grapes genotypes
por: Zheng, Ting, et al.
Publicado: (2021)

Effects of 3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors on Cholesterol Metabolism in Laying Hens
por: Wang, Huanbin, et al.
Publicado: (2023)

Modulation of Dendritic Cell Immunobiology via Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) Reductase
por: Leuenberger, Tina, et al.
Publicado: (2014)

Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells
por: Göbel, Andy, et al.
Publicado: (2019)

An Insight Into Structure, Function, and Expression Analysis of 3-Hydroxy-3-Methylglutaryl-CoA Reductase of Cymbopogon winterianus
por: Devi, Kamalakshi, et al.
Publicado: (2017)

Characterization and Function of 3-Hydroxy-3-Methylglutaryl-CoA Reductase in Populus trichocarpa: Overexpression of PtHMGR Enhances Terpenoids in Transgenic Poplar
por: Wei, Hui, et al.
Publicado: (2019)

7-Acetoxyhorminone from Salvia multicaulis Vahl. as Promising Inhibitor of 3-Hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase
por: Yigitkan, Serkan, et al.
Publicado: (2022)

Anti-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (Anti-HMG CoA) Myopathy With Cardiac Involvement: Presentation, Diagnosis, and Management
por: Liu, Lisa, et al.
Publicado: (2022)

Mutations underlying 3-Hydroxy-3-Methylglutaryl CoA Lyase deficiency in the Saudi population
por: Al-Sayed, Moeenaldeen, et al.
Publicado: (2006)

Enhancing production of ergosterol in Pichia pastoris GS115 by over-expression of 3-hydroxy-3-methylglutaryl CoA reductase from Glycyrrhiza uralensis
por: Liu, Ying, et al.
Publicado: (2014)

Abscisic Acid Regulates the 3-Hydroxy-3-methylglutaryl CoA Reductase Gene Promoter and Ginsenoside Production in Panax quinquefolium Hairy Root Cultures
por: Kochan, Ewa, et al.
Publicado: (2019)

Hypercholesterolemia and 3-Hydroxy 3-Methylglutaryl Coenzyme A Reductase Regulation during Ageing
por: Trapani, Laura, et al.
Publicado: (2009)

Re-evaluation of NCGR Davis Ficus carica and palmata SSR profiles
por: Frost, Richard
Publicado: (2022)

Proteomic Analysis and In Vivo Studies Reveal the Potential Gastroprotective Effects of CHCl(3) and Aqueous Extracts of Ficus palmata
por: Ansari, Sameen Fatima, et al.
Publicado: (2021)

Cloning and Characterisation of the Gene Encoding 3-Hydroxy-3-Methylglutaryl-CoA Synthase in Tripterygium wilfordii
por: Liu, Yu-Jia, et al.
Publicado: (2014)

A newborn screening approach to diagnose 3‐hydroxy‐3‐methylglutaryl‐CoA lyase deficiency
por: Václavík, Jan, et al.
Publicado: (2020)

Analysis of Autoantibodies to 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Using Different Technologies
por: Musset, Lucile, et al.
Publicado: (2014)

Varicose Remodeling of Veins Is Suppressed by 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Inhibitors
por: Eschrich, Johannes, et al.
Publicado: (2016)

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet–associated endoplasmic reticulum membranes
por: Jo, Youngah, et al.
Publicado: (2013)

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon- [Formula: see text] in primary macrophages requires endogenous 25-hydroxycholesterol synthesis
por: Lu, Hongjin, et al.
Publicado: (2015)

Pan‐cancer analysis reveals the oncogenic role of 3‐hydroxy‐3‐methylglutaryl‐CoA synthase 1
por: Zhou, Cheng, et al.
Publicado: (2021)

Pediatric necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies
por: Liang, Wen-Chen, et al.
Publicado: (2017)

Statin-Induced Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (Anti-HMGCR) Myopathy
por: Ghazal, Fatima, et al.
Publicado: (2023)

Cloning, characterization, and functional analysis of acetyl-CoA C-acetyltransferase and 3-hydroxy-3-methylglutaryl-CoA synthase genes in Santalum album
por: Niu, Meiyun, et al.
Publicado: (2021)

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells
por: Elsabrouty, Rania, et al.
Publicado: (2013)

A Case of Dilated Cardiomyopathy Associated with 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG CoA) Lyase Deficiency
por: Leung, Alexander A. C., et al.
Publicado: (2009)

The Association of 3-Hydroxy-3-Methylglutaryl-CoA Reductase, Apolipoprotein E, and Solute Carrier Organic Anion Genetic Variants with Atorvastatin Response among Jordanian Patients with Type 2 Diabetes
por: Alhawari, Hussam, et al.
Publicado: (2020)

Dual Targeting of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Histone Deacetylase as a Therapy for Colorectal Cancer()
por: Wei, Tzu-Tang, et al.
Publicado: (2016)

Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
por: Sasidhar, Manda V., et al.
Publicado: (2017)

Association of Common and Rare Genetic Variation in the 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk
por: Ghouse, Jonas, et al.
Publicado: (2022)

Case report: Diagnostic clues for anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase myopathy in pediatric patients
por: Watanuki, Keisuke, et al.
Publicado: (2023)

Influence of Nutrient (NPK) Factors on Growth, and Pharmacodynamic Component Biosynthesis of Atractylodes chinensis: An Insight on Acetyl-CoA Carboxylase (ACC), 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGR), and Farnesyl Pyrophosphate Synthase (FPPS) Signaling Responses
por: Sun, Jin, et al.
Publicado: (2022)

Novel HMGCS2 pathogenic variants in a Chinese family with mitochondrial 3‐hydroxy‐3‐methylglutaryl‐CoA synthase deficiency
por: Zhang, Pengfei, et al.
Publicado: (2019)

Clinical, Biochemical, Molecular, and Outcome Features of Mitochondrial 3-Hydroxy-3-Methylglutaryl-CoA Synthase Deficiency in 10 Chinese Patients
por: Wu, Shengnan, et al.
Publicado: (2022)

Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston]
por: Singh, Ravi S, et al.
Publicado: (2010)

Ficus palmata Forskål (beles adgi) as a source of milk clotting agent: a preliminary research
por: Sbhatu, Desta Berhe, et al.
Publicado: (2020)

The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells
por: Glynn, Sharon A, et al.
Publicado: (2008)

Species-Specific Expansion and Molecular Evolution of the 3-hydroxy-3-methylglutaryl Coenzyme A Reductase (HMGR) Gene Family in Plants
por: Li, Wei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8rr7qo6l6rnq39p1gecar0u32f