Age Modulates Fe(3)O(4) Nanoparticles Liver Toxicity: Dose-Dependent Decrease in Mitochondrial Respiratory Chain Complexes Activities and Coupling in Middle-Aged as Compared to Young Rats

We examined the effects of iron oxide nanoparticles (IONPs) on mitochondrial respiratory chain complexes activities and mitochondrial coupling in young (3 months) and middle-aged (18 months) rat liver, organ largely involved in body iron detoxification. Isolated liver mitochondria were extracted usi...

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Detalles Bibliográficos
Autores principales: Baratli, Yosra, Charles, Anne-Laure, Wolff, Valérie, Ben Tahar, Lotfi, Smiri, Leila, Bouitbir, Jamal, Zoll, Joffrey, Sakly, Mohsen, Auger, Cyril, Vogel, Thomas, Abdelmelek, Hafedh, Tebourbi, Olfa, Geny, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032731/
https://www.ncbi.nlm.nih.gov/pubmed/24949453
http://dx.doi.org/10.1155/2014/474081

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