Selective Roles of E2Fs for ErbB2- and Myc-mediated Mammary Tumorigenesis

Previous studies have demonstrated that cyclin D1, an upstream regulator of the Rb/E2F pathway, is an essential component of the ErbB2/Ras (but not the Wnt/Myc) oncogenic pathway in the mammary epithelium. However, the role of specific E2fs for ErbB2/Ras-mediated mammary tumorigenesis remains unknow...

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Detalles Bibliográficos
Autores principales: Wu, Lizhao, de Bruin, Alain, Wang, Hui, Simmons, Timothy, Cleghorn, Whitney, Goldenberg, Larry E., Sites, Emily, Sandy, April, Trimboli, Anthony, Fernandez, Soledad A., Eng, Charis, Shapiro, Charles, Leone, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032808/
https://www.ncbi.nlm.nih.gov/pubmed/24276244
http://dx.doi.org/10.1038/onc.2013.511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032808/
https://www.ncbi.nlm.nih.gov/pubmed/24276244
http://dx.doi.org/10.1038/onc.2013.511

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