Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder

The pumpkin seed oil obtained from Cucurbita pepo has been shown to be useful for the treatment of nocturia in patients with urinal disorders in several western countries. In this study, we evaluated the effect of the pumpkin seed oil from Cucurbita maxima on urinary dysfunction in human overactive...

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Autores principales: Nishimura, Mie, Ohkawara, Tatsuya, Sato, Hiroji, Takeda, Hiroshi, Nishihira, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032845/
https://www.ncbi.nlm.nih.gov/pubmed/24872936
http://dx.doi.org/10.4103/2225-4110.124355
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author Nishimura, Mie
Ohkawara, Tatsuya
Sato, Hiroji
Takeda, Hiroshi
Nishihira, Jun
author_facet Nishimura, Mie
Ohkawara, Tatsuya
Sato, Hiroji
Takeda, Hiroshi
Nishihira, Jun
author_sort Nishimura, Mie
collection PubMed
description The pumpkin seed oil obtained from Cucurbita pepo has been shown to be useful for the treatment of nocturia in patients with urinal disorders in several western countries. In this study, we evaluated the effect of the pumpkin seed oil from Cucurbita maxima on urinary dysfunction in human overactive bladder (OAB). Forty-five subjects were enrolled in this study. An extract of pumpkin seed oil from C. maxima (10 g of oil/day) was orally administrated for 12 weeks. After 6 and 12 weeks, urinary function was evaluated using Overactive Bladder Symptom Score (OABSS). Pumpkin seed oil from C. maxima significantly reduced the degree of OABSS in the subjects. The results from our study suggest that pumpkin seed oil extracts from C. maxima as well as from C. pepo are effective for urinary disorders such as OAB in humans.
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spelling pubmed-40328452014-05-28 Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder Nishimura, Mie Ohkawara, Tatsuya Sato, Hiroji Takeda, Hiroshi Nishihira, Jun J Tradit Complement Med Short Communication The pumpkin seed oil obtained from Cucurbita pepo has been shown to be useful for the treatment of nocturia in patients with urinal disorders in several western countries. In this study, we evaluated the effect of the pumpkin seed oil from Cucurbita maxima on urinary dysfunction in human overactive bladder (OAB). Forty-five subjects were enrolled in this study. An extract of pumpkin seed oil from C. maxima (10 g of oil/day) was orally administrated for 12 weeks. After 6 and 12 weeks, urinary function was evaluated using Overactive Bladder Symptom Score (OABSS). Pumpkin seed oil from C. maxima significantly reduced the degree of OABSS in the subjects. The results from our study suggest that pumpkin seed oil extracts from C. maxima as well as from C. pepo are effective for urinary disorders such as OAB in humans. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4032845/ /pubmed/24872936 http://dx.doi.org/10.4103/2225-4110.124355 Text en Copyright: © Journal of Traditional and Complementary Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Nishimura, Mie
Ohkawara, Tatsuya
Sato, Hiroji
Takeda, Hiroshi
Nishihira, Jun
Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder
title Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder
title_full Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder
title_fullStr Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder
title_full_unstemmed Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder
title_short Pumpkin Seed Oil Extracted From Cucurbita maxima Improves Urinary Disorder in Human Overactive Bladder
title_sort pumpkin seed oil extracted from cucurbita maxima improves urinary disorder in human overactive bladder
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032845/
https://www.ncbi.nlm.nih.gov/pubmed/24872936
http://dx.doi.org/10.4103/2225-4110.124355
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