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Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

The rate of transcription elongation plays an important role in the timing of expression of full-length transcripts as well as in the regulation of alternative splicing. In this study, we coupled Bru-seq technology with 5,6-dichlorobenzimidazole 1-β-D-ribofuranoside (DRB) to estimate the elongation...

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Detalles Bibliográficos
Autores principales: Veloso, Artur, Kirkconnell, Killeen S., Magnuson, Brian, Biewen, Benjamin, Paulsen, Michelle T., Wilson, Thomas E., Ljungman, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032854/
https://www.ncbi.nlm.nih.gov/pubmed/24714810
http://dx.doi.org/10.1101/gr.171405.113