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Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression

The development of the human malaria parasite Plasmodium falciparum is controlled by coordinated changes in gene expression throughout its complex life cycle, but the corresponding regulatory mechanisms are incompletely understood. To study the relationship between genome architecture and gene regul...

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Detalles Bibliográficos
Autores principales: Ay, Ferhat, Bunnik, Evelien M., Varoquaux, Nelle, Bol, Sebastiaan M., Prudhomme, Jacques, Vert, Jean-Philippe, Noble, William Stafford, Le Roch, Karine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032861/
https://www.ncbi.nlm.nih.gov/pubmed/24671853
http://dx.doi.org/10.1101/gr.169417.113