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Targeting the PI3K/mTOR Pathway in Pediatric Hematologic Malignancies

A complex interplay of intracellular signaling networks orchestrates normal cell growth and survival, including translation, transcription, proliferation, and cell cycle progression. Dysregulation of such signals occurs commonly in many malignancies, thereby giving the cancer cell a survival advanta...

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Detalles Bibliográficos
Autores principales: Tasian, Sarah K., Teachey, David T., Rheingold, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032892/
https://www.ncbi.nlm.nih.gov/pubmed/24904824
http://dx.doi.org/10.3389/fonc.2014.00108