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Targeting the PI3K/mTOR Pathway in Pediatric Hematologic Malignancies
A complex interplay of intracellular signaling networks orchestrates normal cell growth and survival, including translation, transcription, proliferation, and cell cycle progression. Dysregulation of such signals occurs commonly in many malignancies, thereby giving the cancer cell a survival advanta...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032892/ https://www.ncbi.nlm.nih.gov/pubmed/24904824 http://dx.doi.org/10.3389/fonc.2014.00108 |