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Dihydroartemisinin is a Hypoxia-Active Anti-Cancer Drug in Colorectal Carcinoma Cells
Tumor hypoxia is one main biological factor that drives resistance to chemotherapy and radiotherapy. To develop a novel strategy for overcoming hypoxia-induced therapy resistance, we examined the anti-neoplastic activity of the reactive oxygen donor dihydroartemisinin (DHA) in human colon cancer cel...
Autores principales: | Ontikatze, Teona, Rudner, Justine, Handrick, René, Belka, Claus, Jendrossek, Verena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032948/ https://www.ncbi.nlm.nih.gov/pubmed/24904829 http://dx.doi.org/10.3389/fonc.2014.00116 |
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