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Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland

Expenditures of health care systems are increasing from year to year. Therefore, this study aimed to estimate the difference in costs and benefits of innovative pharmaceuticals launched 2000 onward compared to standard treatment on the national economy of Switzerland in 2010. The approach and formul...

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Autores principales: Pavic, Matea, Pfeil, Alena M., Szucs, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033008/
https://www.ncbi.nlm.nih.gov/pubmed/24904912
http://dx.doi.org/10.3389/fpubh.2014.00048
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author Pavic, Matea
Pfeil, Alena M.
Szucs, Thomas D.
author_facet Pavic, Matea
Pfeil, Alena M.
Szucs, Thomas D.
author_sort Pavic, Matea
collection PubMed
description Expenditures of health care systems are increasing from year to year. Therefore, this study aimed to estimate the difference in costs and benefits of innovative pharmaceuticals launched 2000 onward compared to standard treatment on the national economy of Switzerland in 2010. The approach and formula described in the pilot study by Tsiachristas et al. (1), which analyzed the situation of welfare effects in the Netherlands, served as a model for our own calculations. A literature search was performed to identify cost–utility or cost-effectiveness studies of drugs launched 2000 onward compared to standard treatment. All parameters required for the calculation of welfare effects were derived from these analyses. The base-case threshold value of a quality-adjusted life year was set to CHF 100,000. Overall, 31 drugs were included in the welfare calculations. The introduction of innovative pharmaceuticals since 2000 onward to the Swiss market led to a potential welfare gain of about CHF 781 million in the year 2010. Univariate sensitivity analysis showed that results were robust. Probably because of the higher benefits of new drugs on health and quality of life compared to standard treatment, these drugs are worth the higher costs. The literature search revealed that there is a lack of information about the effects of innovative pharmaceuticals on the overall economy of Switzerland. Our study showed that potential welfare gains in 2010 by introducing innovative pharmaceuticals to the Swiss market were substantial. Considering costs and benefits of new drugs is important.
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spelling pubmed-40330082014-06-05 Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland Pavic, Matea Pfeil, Alena M. Szucs, Thomas D. Front Public Health Public Health Expenditures of health care systems are increasing from year to year. Therefore, this study aimed to estimate the difference in costs and benefits of innovative pharmaceuticals launched 2000 onward compared to standard treatment on the national economy of Switzerland in 2010. The approach and formula described in the pilot study by Tsiachristas et al. (1), which analyzed the situation of welfare effects in the Netherlands, served as a model for our own calculations. A literature search was performed to identify cost–utility or cost-effectiveness studies of drugs launched 2000 onward compared to standard treatment. All parameters required for the calculation of welfare effects were derived from these analyses. The base-case threshold value of a quality-adjusted life year was set to CHF 100,000. Overall, 31 drugs were included in the welfare calculations. The introduction of innovative pharmaceuticals since 2000 onward to the Swiss market led to a potential welfare gain of about CHF 781 million in the year 2010. Univariate sensitivity analysis showed that results were robust. Probably because of the higher benefits of new drugs on health and quality of life compared to standard treatment, these drugs are worth the higher costs. The literature search revealed that there is a lack of information about the effects of innovative pharmaceuticals on the overall economy of Switzerland. Our study showed that potential welfare gains in 2010 by introducing innovative pharmaceuticals to the Swiss market were substantial. Considering costs and benefits of new drugs is important. Frontiers Media S.A. 2014-05-20 /pmc/articles/PMC4033008/ /pubmed/24904912 http://dx.doi.org/10.3389/fpubh.2014.00048 Text en Copyright © 2014 Pavic, Pfeil and Szucs. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Pavic, Matea
Pfeil, Alena M.
Szucs, Thomas D.
Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland
title Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland
title_full Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland
title_fullStr Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland
title_full_unstemmed Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland
title_short Estimating the Potential Annual Welfare Impact of Innovative Drugs in Use in Switzerland
title_sort estimating the potential annual welfare impact of innovative drugs in use in switzerland
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033008/
https://www.ncbi.nlm.nih.gov/pubmed/24904912
http://dx.doi.org/10.3389/fpubh.2014.00048
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