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Efficacy of subcutaneous interferon β-1a on MRI outcomes in a randomised controlled trial of patients with clinically isolated syndromes

AIM: The REbif FLEXible dosing in early MS (REFLEX) study compared several brain MRI outcomes in patients presenting with clinically isolated syndromes suggestive of multiple sclerosis and treated with two dose-frequencies of subcutaneous interferon (IFN) β-1a or placebo. METHODS: Patients were rand...

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Detalles Bibliográficos
Autores principales: De Stefano, Nicola, Comi, Giancarlo, Kappos, Ludwig, Freedman, Mark S, Polman, Chris H, Uitdehaag, Bernard M J, Hennessy, Brian, Casset-Semanaz, Florence, Lehr, Lorenz, Stubinski, Bettina, Jack, Dominic L, Barkhof, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033030/
https://www.ncbi.nlm.nih.gov/pubmed/24292999
http://dx.doi.org/10.1136/jnnp-2013-306289